Hepatoprotective Activity of Bryophyllum pinnatum Leaves (Boiled Extract) on Albino Wistar Rats – in vivo Study

Aim: The aim of this study is to determine the effects boiled Bryophyllum pinnatum leaves on serum liver enzymes after administration alcohol-induced damage in Albino Wistar rats.
 Study Design: Experimental.
 Place and Duration Study: Department Biochemistry, University Calabar (from June August, 2021).
 Methodology: Fresh collected were washed thoroughly with clean water allowed dry at room temperature for 2 hours. 100oC obtain a extract from fresh leaves. Alcohol leaf administered orally period one week each. rats group 3 induced sub-chronic using commonly available alcoholic beverage, blended whiskey dose 1.5 ml per body weight while given extracts week. At end two weeks treatment period, weighed sacrificed their blood analysis (liver function test).
 Results: animals alcohol suffered mild hepatic damage. negative control which was only alcohol, had an increase ALT when compared normal control. treated decrease ALT, AST ALP levels This suggests that contain pharmacologically active compounds can reduce damage.
 Conclusion Recommendations: results show minimal anti-hepatotoxic activities leaves; could be said prevent by toxicity. Further area pharmacology required order establish natural product as agent.